Friendly Fungi: Elucidating the fungal biosynthesis of stipitatic acid
18 May 2012, 6:48 am
(Phys.org) -- In a tale worthy of Sherlock Holmes, scientists in the School of Chemistry at the University of Bristol, UK have solved a biochemical mystery that had previously proven elusive for 70 years: How the fungus Talaromyces stipitatus produces stipitatic acid (6), which is a tropolone, one of an atypical group of fungal natural products – that is, small molecules produced by genetically ...